Omnaris: Adult Dosing

Dosage forms: 50 mcg/spray

allergic rhinitis

2 sprays/nostril qd

Max: 2 sprays/nostril/day

renal dosing

not defined

hepatic dosing

no adjustment

Omnaris: Peds Dosing

Dosage forms: 50 mcg/spray

allergic rhinitis, seasonal

>6 yo

Dose: 2 sprays/nostril qd; Max: 2 sprays/nostril/day; Info: use lowest effective dose

allergic rhinitis, perennial

>12 yo

Dose: 2 sprays/nostril qd; Max: 2 sprays/nostril/day; Info: use lowest effective dose

renal dosing

not defined

hepatic dosing

no adjustment

Omnaris: Contraindications/Cautions

• hypersens. to drug/class/compon.
• nasal septal ulcer, unhealed
• nasal surgery/trauma wound, unhealed
• caution if local or systemic infxn, untreated
• caution if TB infxn
• caution if ocular HSV infxn
• caution if measles/varicella exposure
• caution if incr. IOP
• caution if glaucoma
• caution if cataracts
• caution if adrenal suppression/hypercorticism
• caution if adrenal insufficiency

Omnaris: Drug Interactions

Caution Advised

• chloramphenicol

• clarithromycins

• conivaptan

• delavirdine

• fluvoxamine

• imatinib

• itraconazole

• ketoconazole

• nefazodone

• posaconazole

• protease inhibitors

• telithromycin

• voriconazole

Omnaris: Adverse Reactions

Serious Reactions

• nasal septal perforation (rare)
• nasal/oral candidiasis (rare)
• growth suppression (peds)
• incr. IOP (rare)
• glaucoma (rare)
• cataracts (rare)
• hypercorticism
• adrenal suppression
• hypersensitivity rxn (rare)
• wheezing (rare)

Common Reactions

• headache
• nasopharyngitis
• epistaxis
• pharyngolaryngeal pain
• ear pain

Omnaris: Safety Monitoring

Pregnancy: C

Lactation: Safety Unknown

Monitoring Parameters: nasal exams if tx >several mo; ophthal. exams if cataract/glaucoma hx; height in children/adolescents

Omnaris: Pharmacology

Metabolism: liver extensively; CYP450: 2D6, 3A4 (primary) substrate; Info: prodrug converted to des-ciclesonide; minimal systemic absorption

Excretion: bile/feces 66%, urine <20%; Half-life: unknown

Class: Nasal Steroids

Mechanism Of Action
anti-inflammatory mechanism of action unknown (corticosteroid)

Omnaris: Manufacturer/Pricing

Manufacturer: Sepracor DEA/FDA: Rx

Omnaris: Patient Education

Patient education material for this drug is not currently available.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Omnaris: Pill Pictures

This information is currently unavailable or not applicable for this drug.