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  • Omnaris ciclesonide nasal - Sepracor

    Omnaris: Adult Dosing

    Dosage forms: 50 mcg/spray
    allergic rhinitis
    2 sprays/nostril qd
    Max: 2 sprays/nostril/day
    renal dosing
    not defined
    hepatic dosing
    no adjustment

    Omnaris: Peds Dosing

    Dosage forms: 50 mcg/spray
    allergic rhinitis, seasonal
    >6 yo
    Dose: 2 sprays/nostril qd; Max: 2 sprays/nostril/day; Info: use lowest effective dose
    allergic rhinitis, perennial
    >12 yo
    Dose: 2 sprays/nostril qd; Max: 2 sprays/nostril/day; Info: use lowest effective dose
    renal dosing
    not defined
    hepatic dosing
    no adjustment

    Omnaris: Contraindications/Cautions

    • hypersens. to drug/class/compon.
    • nasal septal ulcer, unhealed
    • nasal surgery/trauma wound, unhealed
    • caution if local or systemic infxn, untreated
    • caution if TB infxn
    • caution if ocular HSV infxn
    • caution if measles/varicella exposure
    • caution if incr. IOP
    • caution if glaucoma
    • caution if cataracts
    • caution if adrenal suppression/hypercorticism
    • caution if adrenal insufficiency

    Omnaris: Adverse Reactions

    Serious Reactions
    • nasal septal perforation (rare)
    • nasal/oral candidiasis (rare)
    • growth suppression (peds)
    • incr. IOP (rare)
    • glaucoma (rare)
    • cataracts (rare)
    • hypercorticism
    • adrenal suppression
    • hypersensitivity rxn (rare)
    • wheezing (rare)
    Common Reactions
    • headache
    • nasopharyngitis
    • epistaxis
    • pharyngolaryngeal pain
    • ear pain

    Omnaris: Safety Monitoring

    Pregnancy: C
    Lactation: Safety Unknown
    Monitoring Parameters: nasal exams if tx >several mo; ophthal. exams if cataract/glaucoma hx; height in children/adolescents

    Omnaris: Pharmacology

    Metabolism: liver extensively; CYP450: 2D6, 3A4 (primary) substrate; Info: prodrug converted to des-ciclesonide; minimal systemic absorption
    Excretion: bile/feces 66%, urine <20%; Half-life: unknown
    Class: Nasal Steroids
    Mechanism Of Action
    anti-inflammatory mechanism of action unknown (corticosteroid)

    Omnaris: Manufacturer/Pricing

    Manufacturer: Sepracor
    DEA/FDA: Rx

    Omnaris: Patient Education

    Patient education material for this drug is not currently available.

    Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

    The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Omnaris: Pill Pictures

    This information is currently unavailable or not applicable for this drug.


    Copyright 1996-2006 Cerner Multum, Inc. Version: 5.05. Revision Date: 10/09/2007
    Last Updated: 10/09/2007

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